Table V.

Quantification of microvesicle numbers in platelet poor plasma from trauma and control groups using dual labelled flow cytometry

	Trauma time 0			Controls
Sample	Median (per µL)	IQR	% of total MV	Median (per µL)	IQR	% of total MV	% of trauma patients >95% CI of controls
CD41+/AV+	177*	65–456	17	86	65–127	24	60
CD235+/AV+	171**	98–290	17†	38	26–78	8	67
AnnV+	573**	364–941	56	215	128–524	53	61
CD31+/41−	16	10–35	2 ^	17	9–34	5	18
CD14+/142+	30	10–47	3	12	9–36	3	47
CD41+/142+	30	9–52	3	13	11–42	4	41
CD45+/142+	27	9–48	2	12	8–45	3	8

Key: AnnV – Annexin V; CI – confidence interval. Trauma cohort data at admission are compared with control data. There are significantly greater numbers of procoagulant MV present (AnnV+; p≤0.001) in the trauma samples which are of both platelet and red cell origin

^*denotes p<0.05

^**denotes p≤0.001

When comparing the distribution of MV subtypes, there is a greater proportion of CD235a+/AnnV+ MV

^†(denotes p=0.02, Mann–Whitney U) and a lower proportion of CD31+/41- MV

^{^}(denotes p=0.004, Mann–Whitney U) in the plasma of trauma patients.