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. 2014 Oct 31;3:10.3402/jev.v3.25625. doi: 10.3402/jev.v3.25625

Table V.

Quantification of microvesicle numbers in platelet poor plasma from trauma and control groups using dual labelled flow cytometry

Trauma time 0 Controls

Sample Median (per µL) IQR % of total MV Median (per µL) IQR % of total MV % of trauma patients >95% CI of controls
CD41+/AV+ 177* 65–456 17 86 65–127 24 60
CD235+/AV+ 171** 98–290 17 38 26–78 8 67
AnnV+ 573** 364–941 56 215 128–524 53 61
CD31+/41− 16 10–35 2 ^ 17 9–34 5 18
CD14+/142+ 30 10–47 3 12 9–36 3 47
CD41+/142+ 30 9–52 3 13 11–42 4 41
CD45+/142+ 27 9–48 2 12 8–45 3 8

Key: AnnV – Annexin V; CI – confidence interval. Trauma cohort data at admission are compared with control data. There are significantly greater numbers of procoagulant MV present (AnnV+; p≤0.001) in the trauma samples which are of both platelet and red cell origin

*

denotes p<0.05

**

denotes p≤0.001

When comparing the distribution of MV subtypes, there is a greater proportion of CD235a+/AnnV+ MV

(denotes p=0.02, Mann–Whitney U) and a lower proportion of CD31+/41- MV

^

(denotes p=0.004, Mann–Whitney U) in the plasma of trauma patients.