Table 1.

Insulin secretion evoked by 3 mM glucose concentration and in the presence of the respective substances

		Ctrl			Gαi2βcko
		Secreted insulin			Secreted insulin
Condition		%Insulin content	SE	n	%Insulin content	SE	n	P
3 mM glucose		0.189	± 0.02	28	0.174	± 0.02	27	n.s.
3 mM glucose	1 μM clonidine	0.153	± 0.05	5	0.064	± 0.01	4	n.s.
	100 nM SST	0.176	± 0.05	4	0.141	± 0.04	3	n.s.
	200 mM palmitate	0.324	± 0.04	2	0.470	± 0.02	2	n.s.
	100 μM l-leucine	0.292	± 0.05	3	0.329	± 0.06	3	n.s.
	10 mM l-arginine	0.075	± 0.02	3	0.143	± 0.03	4	n.s.
	10 mM l-ornithine	0.150	± 0.02	6	0.039	± 0.01	5	n.s.

n.s., not significant; n, set of triplicates.