Fig. 7.

Cardiac responses to chronic pressure overload in WT and TG mice subjected to TAC at 8 wk of age. A–C: LV posterior wall thickness (A), LV end-diastolic internal dimension (B), and LV fractional shortening (C) in WT and TG male mice 8 wk after TAC (n = 9–10) or sham (n = 7–8) surgery. D and E: heart wet weights (D) and lung wet weights (E) normalized to tibia length 8 wk after sham (n = 6) or TAC (n = 6–7) surgery. *P < 0.05 vs. WT sham-operated mice; #P < 0.05 vs. sham surgery in the same genotype.