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. 2014 Aug 29;307(9):H1307–H1316. doi: 10.1152/ajpheart.00280.2014

Fig. 8.

Fig. 8.

Cardiac gene expression in WT and TG mice subjected to TAC at 8 wk of age. A–C: mRNA levels of brain natriuretic peptide (Bnp; A), cardiac sarco(endo)plasmic reticulum Ca2+-ATPase 2 (Serca2; B), and PGC-1α (C). D and E: CS activity (D) and mRNA levels of PGC-1α downstream targets (E) reflecting mitochondrial biogenesis in sham-operated and TAC hearts of WT and TG mice 8 wk after surgery (n = 4 mice/group). The dotted line indicates the WT sham-operated group. *P < 0.05 vs. WT mice with the same treatment; #P < 0.05 vs. sham surgery in the same genotype.