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. 2014 Aug 29;307(9):H1288–H1297. doi: 10.1152/ajpheart.00068.2014

Fig. 2.

Fig. 2.

Effect of heating with and without TRPV family and TRPV4-specific inhibition (RR and RN-1734, respectively) on endothelium-dependent, acetylcholine-induced (ACh) vasorelaxation. A: effect of heat and RR on ACh concentration-response curve. B: effect of heat and RN-1734 on ACh concentration-response curve. C: effect of heat, RR, and endothelial denudation on ACh concentration-response curve. D: effect of heat, RR, and endothelial denudation on ACh concentration-response curve. *Response to concentration significantly different than the same concentration in the 37°C control condition (P < 0.05). †Concentration-response curve significantly different than 37°C control curve (P < 0.05).