Table 3.
Homology (%) of Nucleotides (Top Line) and Amino Acids (Bottom Line) Among Each Canine Interferon Subtype and Other Reported IFNE-λs
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | *** | 5.6 | 8 | 9.3 | 9.3 | 17.2 | 9.3 | 3.3 | 3.3 | 3.8 | 4.8 | 11.5 | 8.1 | 94.4 | 5.2 | 12.4 | 14.4 | 99.4 | 10.2 | 9.8 | 9.4 | 10 | 7 | BaboIFN-λ4 |
| 2 | 21.8 | *** | 72.9 | 3 | 3 | 18.2 | 3 | 2.3 | 4.8 | 6.4 | 6.6 | 75.9 | 46.9 | 6.9 | 76.7 | 74.8 | 74.7 | 6.5 | 68.4 | 66.7 | 11.1 | 75.5 | 72.7 | BatIFN-λ1 |
| 3 | 25.1 | 66 | *** | 6.9 | 4.1 | 18 | 6.9 | 3.9 | 2.8 | 7.2 | 3.6 | 77.8 | 52.6 | 8.5 | 71.3 | 80.1 | 79.4 | 8.1 | 72.5 | 70.3 | 7.8 | 74 | 80.1 | BatIFN-λ2 |
| 4 | 7.8 | 9.1 | 6.4 | *** | 99.6 | 96.3 | 99.6 | 43.1 | 35.6 | 3.6 | 13.8 | 5.7 | 12.3 | 9.1 | 3 | 3 | 3.2 | 9.6 | 3 | 3 | 2.8 | 5.3 | 5.1 | CaIFN-α5 |
| 5 | 7.8 | 9.1 | 6.4 | 99.5 | *** | 96.3 | 99.6 | 44.6 | 35.5 | 3.6 | 13.8 | 5.9 | 5.9 | 9.1 | 3 | 3 | 3.2 | 9.6 | 3 | 3 | 2.8 | 5.3 | 5.1 | CaIFN-α6 |
| 6 | 7.8 | 9.1 | 3.2 | 93 | 93.6 | *** | 96.3 | 23.4 | 20.9 | 20.2 | 21 | 17.8 | 18.2 | 16.3 | 18.2 | 18.9 | 19.3 | 17.6 | 18.4 | 16.8 | 19.6 | 18.6 | 19.9 | CaIFN-α7 |
| 7 | 7.8 | 9.1 | 6.4 | 98.9 | 99.5 | 93 | *** | 44.4 | 35.5 | 3.6 | 13.8 | 8.7 | 5.9 | 9.1 | 3 | 3 | 3.2 | 9.6 | 3 | 3 | 2.8 | 5.3 | 5.1 | CaIFN-α8 |
| 8 | 6.7 | 5.9 | 5.4 | 26.9 | 26.9 | 22 | 26.3 | *** | 40.6 | 3.6 | 14.6 | 2.1 | 4.1 | 3.7 | 3.2 | 2.1 | 3.9 | 3.3 | 2.9 | 2.9 | 5 | 2 | 3.2 | CaIFN-β1 |
| 9 | 1.7 | 5.9 | 5.3 | 27.8 | 27.8 | 28.3 | 27.3 | 32.3 | *** | 3 | 11.3 | 4.3 | 7.5 | 2.6 | 2.7 | 2.7 | 2.7 | 3.5 | 2.8 | 6.9 | 5.6 | 2.5 | 2.8 | CaIFN-ζ |
| 10 | 2.4 | 11.4 | 3 | 10.2 | 10.2 | 10.8 | 10.2 | 7.2 | 4.2 | *** | 4.2 | 4.2 | 5.8 | 3 | 6.4 | 4.6 | 4.6 | 3.8 | 9.2 | 9 | 2.4 | 6.2 | 8.4 | CaIFN-γ |
| 11 | 4.5 | 4.2 | 3.6 | 24.6 | 24.6 | 25.1 | 24.6 | 26.9 | 31.6 | 12.7 | *** | 2.3 | 3.9 | 5.4 | 2.3 | 6.5 | 6.4 | 4.8 | 6.4 | 4.3 | 4.6 | 3.6 | 6 | CaIFN-κ |
| 12 | 24 | 70 | 69.5 | 4.8 | 4.8 | 4.8 | 4.8 | 5.9 | 5.9 | 10.2 | 4.2 | *** | 48.5 | 8.3 | 80.6 | 77.8 | 76.4 | 11.9 | 70.9 | 69.1 | 8.5 | 82.7 | 77.1 | CaIFN-λ |
| 13 | 17.3 | 31.7 | 33.3 | 4.8 | 4.8 | 4.8 | 5.4 | 7.5 | 5.9 | 4.8 | 5.9 | 35.5 | *** | 7.8 | 45.3 | 49 | 49.4 | 8 | 15.2 | 11.2 | 8.1 | 49.9 | 50.4 | ChIFN-λ3 |
| 14 | 91.6 | 22.9 | 26.8 | 7.3 | 7.3 | 6.7 | 7.3 | 6.1 | 1.7 | 6.6 | 5 | 25.7 | 21.8 | *** | 10.6 | 10.9 | 10.9 | 94.8 | 10.9 | 10 | 3.1 | 7.8 | 7.6 | ChimpIFN-λ4 |
| 15 | 24.6 | 67.5 | 63.6 | 5.3 | 5.3 | 8 | 5.3 | 5.4 | 4.3 | 6.6 | 7 | 73.2 | 29.6 | 25.7 | *** | 75.8 | 77.3 | 10 | 67.2 | 64.9 | 5.6 | 79 | 73.5 | HuIFN-λ1 |
| 16 | 22.3 | 63.4 | 68.7 | 9.1 | 9.1 | 13.4 | 9.1 | 1.6 | 8 | 8.4 | 2.5 | 64.7 | 31.7 | 22.3 | 69.5 | *** | 98.1 | 12.8 | 75.6 | 73.2 | 11.5 | 73.4 | 77.6 | HuIFN-λ2 |
| 17 | 22.3 | 64.9 | 69.2 | 9.6 | 9.6 | 13.4 | 9.6 | 8.1 | 14.4 | 9 | 3.1 | 67.9 | 32.8 | 22.3 | 71.9 | 95.9 | *** | 14.8 | 75.9 | 73.5 | 11.5 | 74 | 78.9 | HuIFN-λ3 |
| 18 | 98.9 | 22.3 | 25.1 | 7.3 | 7.3 | 6.7 | 7.3 | 6.7 | 7.3 | 2.4 | 5 | 24 | 17.3 | 92.7 | 24 | 23.5 | 23.5 | *** | 10.4 | 9.8 | 9.4 | 8.7 | 7.2 | MaIFN-λ4 |
| 19 | 21.8 | 56 | 57.5 | 6.4 | 6.4 | 9.1 | 15 | 3.2 | 11.2 | 10.8 | 4.7 | 57.4 | 32.3 | 22.3 | 56.5 | 64.2 | 64.8 | 21.8 | *** | 97.1 | 7.2 | 68.4 | 76.3 | MuIFN-λ2 |
| 20 | 20.1 | 53.4 | 53.9 | 10.2 | 10.2 | 10.2 | 10.2 | 2.2 | 10.7 | 9 | 2.6 | 53.7 | 30.6 | 20.1 | 53.4 | 61.1 | 61.7 | 20.1 | 93.3 | *** | 7.2 | 66.8 | 74.4 | MuIFN-λ3 |
| 21 | 18.4 | 20.1 | 23.5 | 8.9 | 8.9 | 4.5 | 8.9 | 6.1 | 8.4 | 6.6 | 2.8 | 23.5 | 23.5 | 20.1 | 19 | 23.5 | 24.6 | 17.9 | 21.8 | 22.3 | *** | 7.2 | 5.2 | SiIFN-λ3 |
| 22 | 20.7 | 61.8 | 66.5 | 7.5 | 7.5 | 7 | 7.5 | 4.8 | 6.4 | 7.2 | 3.1 | 77.4 | 30.6 | 21.8 | 72.8 | 61.3 | 64.4 | 20.7 | 52.9 | 50.8 | 21.2 | *** | 74.1 | SwIFN-λ1 |
| 23 | 24 | 60.7 | 70.3 | 7 | 7 | 7 | 7 | 4.3 | 9.1 | 7.2 | 5.1 | 65.8 | 30.6 | 25.7 | 60 | 68.7 | 70.3 | 24 | 61.7 | 58.5 | 20.7 | 60.2 | *** | SwIFN-λ3 |
***
Same sequence.