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. 2014 Nov 3;4:6885. doi: 10.1038/srep06885

Figure 3. Atoh1-rtTA activity in the cochlea.

Figure 3

Representative confocal images of mCherry+ve (red) cells in the middle turn of each founder line breed with the TetO-mCherry reporter at P3 (A–E) and corresponding merged images where HCs were labeled with myosin VIIa (Myo7a, green) (A′–E′). Representative confocal images of LacZ+ve (red) cells in the middle turn of each founder line breed with the TetO-LacZ reporter at P3 (F–J) and corresponding merged images where HCs were labeled with Myo7a (green) (F′–J′). (K) Percentage of Myo7a+ve cells that express mCherry in each founder line, normalized to the number of total Myo7a+ve cells in the same region. (L) Percentage of Myo7a+ve cells that express LacZ in each founder line, normalized to the number of total Myo7a+ve cells in the same region. Data are expressed as mean ± S.E.M for an n of 3–4. IHC, inner hair cells; OHC, outer hair cells. Scale bar: 50 μm.