Table 2.
Frequency of cardiometabolic GxE and GWAS SNPs under positive selection
| Dataset, all cardiometabolic traits | # LD blocks | # with Fst or iHS (%) | p | # with Fst (%) | p | # with iHS (%) | P |
|---|---|---|---|---|---|---|---|
| nonGxE GWAS |
549 |
88 (16.0) |
0.61 |
21 (3.8) |
0.66 |
70 (12.8) |
0.44 |
| GxE | 178 | 30 (16.9) | 8 (4.5) | 22 (12.4) |
p-value based on two-sample z-test.