Table 1.
Demographic and Caregiver Characteristics for AMP Youth Included in Analyses, and HIV-related Characteristics of Included PHIV Youth
| Characteristic | HIV-Infected (PHIV) (n=295) |
HIV-Exposed Uninfected (HEU) (n=167) |
p-value |
|---|---|---|---|
| Age in years (Mean, SD) | 13.1 (2.6) | 11.3 (2.4) | <0.001 |
| Male | 46% | 52% | 0.21 |
| Black or African American | 73% | 68% | 0.29 |
| Hispanic | 21% | 29% | 0.07 |
| Low household income | 42% | 60% | <0.001 |
| Low caregiver education | 25% | 31% | 0.28 |
| Biological parent caregiver | 47% | 81% | <0.001 |
| Caregiver IQ < 85 | 36% | 44% | 0.17 |
| Caregiver IQ missing | 21% | 17% | - |
| Child ever hospitalized | 22% | 16% | 0.11 |
| Child talked before age 2 | 90% | 92% | 0.50 |
| HIV Disease Markers | |||
| CD4 Count, median (IQR) | 683 (490, 944) | - | - |
| CD4%, median (IQR) | 34 (25,39) | - | - |
| HIV VL >400 copies/mL | 28% | - | - |
| Nadir CD4% <15% | 32% | - | - |
| Log peak VL, median (IQR) | 5.46 (4.95, 5.88) | - | - |
| CDC Class C diagnosis, n (%) | 78 (26%) | - | - |
| Encephalopathy, n (%) | 34 (12%) | - | - |
| Current ARV Regimen | |||
| HAART with PI, n (%) | 214 (73%) | - | - |
| HAART w/o PI, n (%) | 51 (17%) | - | - |
| non-HAART ARV, n (%) | 12 (4%) | - | - |
| no ARVs | 17 (6%) | - | - |
| Cumulative years on ARVs, median, IQR | 9.13 (5.65, 10.44) | - | - |
PHIV = perinatally acquired HIV; HEU = HIV exposed, uninfected; SD=standard deviation; CDC= Centers for Disease Control; VL= viral load, IQR= interquartile ration; HAART= highly active antiretroviral therapy; ARV= antiretroviral.