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eIF2α and E-site tRNA and Possible Locations of eIF2β, Related to Figure 6
(A) eIF2α mimics E-site tRNA. An E-site tRNA (from 2J00) and eIF2α are shown superimposed relative to their positions in the E-site.
(B) Possible locations of eIF2β in the complex. The β subunits from two different archaeal aIF2 crystal structures (from 3CW2, in red and from 2D74, in pink) have been modeled in the py48S PIC by superimposing the aIF2γ subunit onto our fitted eIF2γ subunit.
