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. 2014 May 26;27(3-4):163–174. doi: 10.1293/tox.2014-0007

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©2014 The Japanese Society of Toxicologic Pathology

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License.

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Fig. 6. — Immunohistochemistry for proliferative activity and oxidative stress in the liver. Proliferating cell nuclear antigen (PCNA) signals can be seen in the nuclei of hepatocytes of control (a) and green tea extract (GTE)-exposed rats (b). Note that more positive cells can be seen in the rats 48 hrs after GTE exposure (b). No thymidine glycol (TG) signals can be seen in control rats (c), while TG signals in the nuclei of hepatocytes were detected in the rats 48 hrs after GTE exposure (d). No malondialdehyde (MDA) signals can be seen in control rats (e), while positivity for MDA in the hepatocellular cytoplasm was detected in the rats 48 hrs after GTE exposure (f). C: central vein. *Glisson’s sheath. ×200.