Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TGR5-mediated release of GLP-1 and PYY by oleanolic acid (OA). Cells transfected with control siRNA or TGR5-specific siRNA for 48 h and then treated with OA (10 μM) for 30 min. Release of GLP-1 (A) and PYY (B) into the medium was measured by ELISA. Inset: Down regulation of TGR5 expression in cells transfected with TGR5 siRNA was determined by western blot. Results are expressed as pg/100 ml. Values are mean ± s.e.m. of 5 experiments. **p < 0.001 vs. basal.
