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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: Mol Cancer Ther. 2013 Nov 26;13(2):307–315. doi: 10.1158/1535-7163.MCT-13-0324

Figure 4. NMS-P715 selectively inhibits growth of PDAC cells. A. Left panel.

Figure 4

Dose effect of NMS-P715 on viability of BxPC-3, PANC-1 and ASC cells after 72h. 0= vehicle control. Right panel: NMS-P715 IC50 values for BxPC-3, PANC-1 and ASCs after 72h. B. Gemcitabine IC50 values for BxPC-3, PANC-1 and ASCs after 72h. C. BxPC-3, PANC-1 and ASC cells were grown at low density (200 cells/ well) for 6 days in medium supplemented with NMS-P715 (μmol/L) or DMSO control (0) as indicated. Cell growth was measured by colorimetric assay. ASC data represent mean of 5 (A) or 3 (B, C) independent isolates. Data were collected from three (A, B) or two (C) independent experiments. Significance was measured by t-test.