Figure 2.
A more realistic scheme of coupled cardiac cells considering discontinuous properties. The cell membrane (M) is represented by a series of resistor-capacitor circuits, connecting the extracellular space (ES) with the intracellular space (IS). They are interconnected within one cell via extracellular (ro) and intracellular (ri) resistors. Gap junction resistance (RGJ) connects the intracellular spaces of adjacent cells, while extracellular coupling is realized via the resistance of the extracellular cleft (Rcleft).