Skip to main content
. 2014 Nov 3;5:424. doi: 10.3389/fphys.2014.00424

Figure 3.

Figure 3

Connexins are four-transmembrane proteins with two extracellular loops and one intracellular loop. They build hexameric connexons (hemichannels), which dock to a connexon of an adjacent cell forming a complete, dodecameric gap junction channel. M, cell membrane; ES, extracellular space; IS, intracellular space.