Table 1.
Cognitive outcome measures of Zembrin effects on neurobattery tests after 3 weeks of Zembrin treatment and placebo treatment.
| Outcome measure | Mean score and SEM at baseline and after Zembrin and after placebo treatment | ||||||
|---|---|---|---|---|---|---|---|
| CNS Vital Signs Key domains: |
Baseline | After 3 weeks Zembrin | After 3 weeks of placebo | F values | P values | ||
| (N = 17) | [% change] | (N = 18) | [% change] | ||||
| Neurocognitive index (NCI) | 36.3 (4.5) | 43.9 (6.8) | [7.6] | 47.2 (7.7) | [10.9] | F = .992 | P = 0.376 |
| Composite memory | 38.9 (5.3) | 32.9 (8.5) | [−6.0] | 41.0 (9.0) | [2.1] | F = .269 | P = 0.765 |
| Verbal memory | 36.9 (5.1) | 41.6 (7.7) | [4.7] | 43.7 (8.9) | [6.8] | F = .302 | P = 0.740 |
| Visual memory | 45.6 (5.5) | 29.5 (8.6) | [−16.1] | 39.6 (7.2) | [−6.0] | F = 1.403 | P = 0.253 |
| Processing speed | 56.7 (5.7) | 77.4 (6.8) | [20.7] | 54.7 (8.8) | [−2.0] | F = 2.557 | P = 0.085 |
| Executive function | 36.8 (5.4) | 60.8 (6.6) | [24.0] | 50.1 (7.7) | [13.3] | * F = 3.603 | * P = 0.032 |
| Psychomotor speed | 54.8 (5.6) | 60.4 (8.2) | [5.6] | 52.4 (8.5) | [−2.4] | F = .252 | P = 0.778 |
| Reaction time | 45.8 (5.1) | 58.1 (6.3) | [12.3] | 59.1 (6.8) | [13.3] | F = 1.686 | P = 0.193 |
| Complex attention | 38.5 (5.3) | 46.2 (7.8) | [7.7] | 44.9 (8.5) | [6.4] | F = .407 | P = 0.667 |
| Cognitive flexibility | 35.4 (5.3) | 60.2 (6.5) | [24.8] | 49.7 (7.5) | [14.3] | F = 4.016 | * P = 0.022 |
*Statistically different at P < 0.05 two-tailed.