Table 3.
List of ER stress-related genes with significant expression in SMMC-7721 cells (fold change ≥1.5-fold).
Probe set ID | Gene symbol | Control | G418 | ATSE | 1/2(G418 + ATSE) | ATSE/control |
---|---|---|---|---|---|---|
7964460 | DDIT3 | 106 | 274 | 525 | 546 | 4.94 |
8076481 | CYB5R3 | 262 | 209 | 539 | 279 | 2.06 |
8139003 | HERPUD2 | 186 | 263 | 323 | 271 | 1.74 |
8042107 | VRK2 | 536 | 973 | 884 | 1075 | 1.65 |
8156838 | SEC61B | 299 | 566 | 469 | 638 | 1.57 |
8128650 | SEC63 | 776 | 954 | 522 | 653 | −1.50 |
8062174 | ERGIC3 | 984 | 1042 | 662 | 686 | −1.50 |
7958644 | ATP2A2 | 575 | 769 | 382 | 536 | −1.50 |
7989619 | PPIB | 1595 | 2090 | 989 | 2036 | −1.61 |
8084634 | DNAJB11 | 323 | 442 | 196 | 535 | −1.62 |
7981335 | HSP90AA1 | 1428 | 2906 | 831 | 2147 | −1.72 |
8178498 | HLA-B | 327 | 268 | 190 | 246 | −1.72 |
7958130 | HSP90B1 | 1426 | 2138 | 744 | 2022 | −1.92 |
8091954 | GOLIM4 | 641 | 378 | 329 | 364 | −1.95 |
7983274 | PDIA3 | 855 | 1271 | 437 | 949 | −1.96 |
8023561 | LMAN1 | 735 | 816 | 372 | 690 | −1.98 |
7904881 | PDIA3P | 889 | 1360 | 440 | 980 | −2.02 |
8164165 | GRP78 | 1317 | 2308 | 580 | 2346 | −2.27 |
8160914 | VCP | 333 | 318 | 114 | 278 | −2.91 |
G418 (0.45 mg/mL); ATSE: Akebia trifoliate seed extract (0.625 mg/mL); 1/2(G418 + ATSE): a combination of half dose of each accordingly.