Table 1.

Genetic interaction of lin-42(0) and let-7-family genes

Genotype*	Animals with L3-molt alae (%)					Animals with L4-molt alae (%)
	Full	Partial†	None	Quality‡	n	Full	Partial†	None	Quality‡	n
Wild-type (N2)	0	0	100	+++	10	100	0	0	+++	10
lin-42	66	32	2	+++	87	ND	ND	ND	ND
let-7 unc-3	ND	ND	ND	ND		11	26	63	+	38
lin-42; let-7 unc-3	0	15	85	++/+	62	83	14	3	+++	59
lin-42; unc-3	74	24	3	+++	34	ND	ND	ND	ND
lin-42; mir-48	0	35	65	+++/+	43	ND	ND	ND	ND
lin-42; mir-241	85	15	0	+++	26	ND	ND	ND	ND
lin-42; mir-84	73	27	0	+++/++	22	ND	ND	ND	ND
mir-48 mir-241	ND	ND	ND	ND		2	88	19	++	42
lin-42; mir-48 mir-241	0	0	100	—	25	97	3	0	+++	29
mir-48 mir-241; mir-84	ND	ND	ND	ND		0	57	43	++/+	35
lin-42; mir-48 mir-241; mir-84	0	2	98	+	41	83	17	0	+++	35
lin-42; mir-48 mir-241; let-7 unc-3	0	13	87	+	30	19	22	59	+	37

ND, not determined.

^*The following null alleles were used: lin-42(ox461), let-7(mn112), mir-48 mir-241(nDf51), mir-48(n4097), mir-84(n4037), mir-241(n4316).

^†Partial indicates that ≥1 of 16 seam cells scored per animal lacked alae in the overlying cuticle, resulting in gaps.

^‡Alae varied in quality between strains but was of consistent quality within strains, from +++ (wild-type quality) to + (poor, indistinct alae quality).