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A possible model of Sup35NM amyloid. Residues in blue are found to have in-register parallel structure and those in red are not. The Ile residues in green were changed to Leu in all mutants as was Ile239, except when labeling Ile239 itself. The data suggest that each molecule in the in-register β-sheet contributes several β-strand segments and several turns or loops. The underlined regions may be β-strands and possible loop/turn regions are shown.
