Table 1.

Experimental stroke models and mortality rates in aged rats.

Strain	MCA occlusion	Age (mo)	Ischemia	Mortality (%)	Localization	Anesthetic	Reference
Wistar	Thermocoagulation	32	Permanent	NA	Neocortical	Halothane	Davis et al. (1995)
Wistar	Intraluminal nylon monofilament	27	Permanent or reversible	10	Necortical & striatal	Halothane	Sutherland et al. (1996)
Wistar	Photothrombosis	24	Permanent	4	Neocortical	Halothane	Zhao et al. (2005)
Fischer	Photothrombosis non-localized	24	Reversible	16	Neocortical	Chloral hydrate	Futrell et al. (1991)
Wistar	Photothrombosis	24	Permanent	4	Neocortical	Halothane	Zhao et al. (2005)
Wistar	Endothelin-1	20–23	Reversible	13.3	Neocortical	Isoflurane	Soleman et al. (2010)
Wistar	ECA embolization	18–20	Spontaneous reperfusion	33	Necortical & striatal	Isoflurane	Zhang et al. (2013)
Sprague-Dawley (m)	Vascular clip/hook	18–20	Reversible	25	Neocortical	Halothane	Popa-Wagner et al. (1998)
Sprague-Dawley (f)	ECA embolization	18	rt-PA reperfusion	33	Neocortical	Ketamine	Dinapoli et al. (2006)
Wistar	ECA embolization	18	Spontaneous reperfusion	47	Necortical & striatal	Halothane	Zhang et al. (2005)

NA, not assessed; ECA, external carotid artery; f, female; m, male.