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. Author manuscript; available in PMC: 2014 Nov 3.
Published in final edited form as: Ann Biomed Eng. 2011 Dec 28;40(5):1170–1181. doi: 10.1007/s10439-011-0494-z

Figure 2. The effect of glutamate and memantine treatment on the average synchronization index value of electrodes.

Figure 2

A representative MEA for each condition is shown. ASI = average synchronization index. The location of the ASI value for each electrode represents the actual physical location of the electrode on the MEA. Column 1 shows the ASI values prior to drug treatment, column 2 shows the ASI values 24 hours after drug treatment, and column 3 represents the change in the average synchronization of each electrode as a result of drug treatment. In the left and middle columns, a red color designates that that electrode has a high ASI, indicating that the neurons on that electrode fire in synchrony with neurons on other electrodes. A dark blue color designates that the neurons whose action potentials are recorded on that electrode do not fire with a high degree of synchrony with many neurons on other electrodes. In the third column, a yellow color indicates an increase in the ASI, a pale green color represents no change in the ASI, and a blue color represents a decrease in the ASI.