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. Author manuscript; available in PMC: 2015 Aug 15.
Published in final edited form as: J Comp Neurol. 2014 Apr 12;522(12):2691–2706. doi: 10.1002/cne.23576

Figure 2.

Figure 2

Pallial-like progenitors generated by ES-derived progenitors are molecularly heterogeneous. A,B: Half of nestin-expressing progenitors coexpress Pax6 (A) or Sox6 (B). C: About 20% of progenitors express both Pax6 and Sox6. D,E: Most Pax6 (D) and Sox6 (E) pallial progenitors coexpress Otx2. F: Ngn2 is expressed by some Pax6-low or -negative progenitors. G: Mash1/nestin subpallial-like progenitors represent ~10% of cells. H–J: Ventralized ES cells lose Pax6 expression (H) and increase subpallial Nkx2.1 (I) and Gsh2 (J). K,L: Pax6/Mash1 (K) and Sox6/Mash1 (L) cellular subsets are mostly distinct. A magenta-green version of this figure is available online in the Supporting Information. Scale bar = 10 µm.