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. 2014 Nov 3;9(11):e109866. doi: 10.1371/journal.pone.0109866

Figure 3. Preparation of DOTA-conjugated mAb.

Figure 3

A. Scheme of the synthesis of DOTA-conjugated mAb. B. HPLC analysis of original and DOTA-conjugated mAbs. C. Evaluation of CTLA-4 binding activity of DOTA-anti-CTLA-4 mAb. Data are expressed as means ± SEM.