Table 4.
Genes with a significant association between CNV and survival time in SQCC tumors in the TCGA dataset (31). Top genes are identified based on P-value. Hazard ratios and their confidence intervals are shown. Significant hazard ratios are marked with an asterisk (*).
| GENE NAME | P-VALUE | GAIN-HAZARD (95% CI) | LOSS-HAZARD (95% CI) |
|---|---|---|---|
| C14orf173 | 0.0007 | 2.7851 [1.61, 4.81]* | 1.3415 [0.77, 2.32] |
| BRMS1L | 0.0007 | 2.7851 [1.61, 4.81]* | 1.3415 [0.77, 2.32] |
| CHURC1 | 0.0007 | 2.7851 [1.61, 4.81]* | 1.3415 [0.77, 2.32] |
| NEK9 | 0.0007 | 2.7851 [1.61, 4.81]* | 1.3415 [0.77, 2.32] |
| CIDEB | 0.0007 | 2.7851 [1.61, 4.81]* | 1.3415 [0.77, 2.32] |
| SERPINA3 | 0.0007 | 2.7851 [1.61, 4.81]* | 1.3415 [0.77, 2.32] |
| C14orf172 | 0.0008 | 2.7625 [1.59, 4.77]* | 1.3195 [0.76, 2.28] |
| PTPRU | 0.0013 | 0.7796 [0.49, 1.23] | 0.2738 [0.12, 0.61]* |
| SEMA3F | 0.0014 | 0.4337 [0.24, 0.76]* | 1.1128 [0.54, 2.28] |
| TADA3L | 0.0015 | 0.3342 [0.19, 0.57]* | 0.4007 [0.18, 0.86]* |
| CCNB1IP1 | 0.0016 | 2.6560 [1.52, 4.62]* | 1.3451 [0.77, 2.34] |
| C14orf79 | 0.0016 | 2.6560 [1.52, 4.62]* | 1.3451 [0.77, 2.34] |
| UPB1 | 0.0016 | 0.3726 [0.20, 0.66]* | 0.7158 [0.42, 1.20] |
| SH3BP1 | 0.0016 | 0.3726 [0.20, 0.66]* | 0.7158 [0.42, 1.20] |
| TCF20 | 0.0016 | 0.3726 [0.20, 0.66]* | 0.7158 [0.42, 1.20] |
| MUSTN1 | 0.0020 | 0.4559 [0.25, 0.80]* | 1.1888 [0.57, 2.47] |
| ZC3H14 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| C14orf50 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| TDP1 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| C14orf24 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| KIAA0831 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| PTGER2 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| FOXN3 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| PRMT5 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| RIPK3 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| ZFP36L1 | 0.0021 | 2.5397 [1.46, 4.39]* | 1.2468 [0.71, 2.16] |
| LGR6 | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| RFX5 | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| CD1D | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| FLVCR1 | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| MRPS14 | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| DAB1 | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| PUSL1 | 0.0022 | 0.9346 [0.59, 1.47] | 0.3007 [0.13, 0.66]* |
| CSDC2 | 0.0022 | 0.3736 [0.20, 0.67]* | 0.7728 [0.46, 1.29] |
| P2RXL1 | 0.0022 | 0.3736 [0.20, 0.67]* | 0.7728 [0.46, 1.29] |
| PNPLA3 | 0.0022 | 0.3736 [0.20, 0.67]* | 0.7728 [0.46, 1.29] |
| CSNK1E | 0.0022 | 0.3736 [0.20, 0.67]* | 0.7728 [0.46, 1.29] |
| CCDC117 | 0.0022 | 0.3736 [0.20, 0.67]* | 0.7728 [0.46, 1.29] |
| ATP8B2 | 0.0023 | 1.0134 [0.64, 1.59] | 0.3111 [0.13, 0.69]* |
| NPPB | 0.0023 | 1.0111 [0.64, 1.58] | 0.3108 [0.13, 0.69]* |