Table 6.
mRNA prognostic biomarkers identified in our previous studies7,38,39 ranked as top driver genes in good prognosis SQCC patients.
| GENE NAME | MODULATOR? (# MODULES)* | MODULATED BY | REFERENCE |
|---|---|---|---|
| OGT | No | C6orf134 | 38 |
| CCDC99 | No | CCL19 | 39 |
| CD27 | No | CCL19 | 39 |
| DAG1 | No | C6orf134 | N/A# |
| XPO1 | No | PRMT5 | 39 |
| C8orf70 | No | RB1 | 39 |
| AKAP13 | No | RB1 | 38 |
| MSX2 | No | RB1 | 38 |
| ADH1B | Yes (4) | STAT4 | 7 |
| ANXA6 | No | VASH1 | 7 |
| CCL19 | Yes (4) | No Modulator | 7 |
| CLIC2 | No | ADH1B | 7 |
| COL14A1 | No | VASH1 | 7 |
| FHL1 | Yes (1) | VASH1 | 7 |
| ICA1 | No | RB1 | 7 |
| IRF3 | No | C6orf134 | 7 |
| IVD | No | VASH1 | 7 |
| SLC39A8 | No | ADH1B | 7 |
| SPIN1 | No | PRMT5 | 7 |
| TAF4 | No | C6orf134 | 7 |
| VASH1 | Yes (4) | ADH1B | 7 |
| HFE | No | C14orf50 | 39 |
| RB1 | Yes (7) | No Modulator | 7 |
| STAT6 | No | CCL19 | 47 |
| ZNF638 | No | C6orf134 | 38 |
| UBE1L2 | no | C6orf134 | 39 |
Notes:
*
If a gene is a modulator (driver gene), the number of modules regulated by it is listed in parentheses.
#
Unpublished mRNA prognostic biomarkers associated with NSCLC outcome.