Table I.

Changes in the levels of uric acid in the rats of the different groups (mean ± SD).

Group	YEP + OA	Rosuvastatin (mg/kg/day)	Allopurinol (mg/kg/day)	Uric acid (μmol/l)
				Week 0	Week 2	Week 4	Week 6
Blank control	-	-	-	43.99±0.59	49.50±2.64cegik	45.31±1.66cdgi	45.14±0.89cfi
Model	✓	-	-	46.71±3.88	248.00±8.18begik	352.25±5.35begik	216.00±6.15begik
Rosuvastatin	✓	2.50	-	43.29±0.90	124.75±16.79bc	118.50±4.65begik	89.75±2.04bcegk
	✓	5.00	-	44.63±1.09	129.00±5.05bc	100.50±1.72begik	62.25±6.20acdhj
	✓	10.00	-	42.28±0.61	112.75±13.89bc	67.00±10.27ace	41.75±4.76cfi
Allopurinol	✓	-	53.75	40.69±5.51	103.75±10.03bc	59.25±2.86ace	44.75±4.32cfi

^aP<0.05 and

^bP<0.01, vs. blank control group;

^cP<0.01, vs. model group;

^dP<0.05 and

^eP<0.01, vs. 10 mg/kg/day rosuvastatin group;

^fP<0.05 and

^gP<0.01, vs. 5 mg/kg/day rosuvastatin group;

^hP<0.05 and

ⁱP<0.01, vs. 2.5 mg/kg/day rosuvastatin group;

^jP<0.05 and

^kP<0.01, vs. allopurinol group.

YEP, yeast extract powder; OA, oxonic acid.