Table 1. Description of different steps of human filtration of pipeline utilized to compare sensitivity/specificity of detection and performance of runtime and computational resources of the simulated reads.
Quality Filter | Fast Alignment | Data Compression | Sensitive Alignment | Repeat DB | |
mg_bw2 | yes | bowtie2 | - | - | - |
mg_bwa | yes | bwa | - | - | - |
mg_dc | yes | bwa | - | stampy | yes |
mgall_bw2 | yes | bowtie2 | Yes | stampy | yes |
mgall_bwa | yes | bwa | Yes | stampy | yes |
Dash (-) represents that the option was not utilized.