Figure 4. Placental COX-1 and COX-2 expression after S. Enteritidis enterocolitis.
Pregnant mice received 20 mg of streptomycin 24 h before intragastric infection with 3–4×103 CFU of S. Enteritidis (day 15 of gestation). A group of non infected pregnant mice was included as control. Placentas (healthy and infected) were obtained on day 18 of gestation. The relative COX-1 and COX-2 mRNA amount was determined by qPCR and related to mRNA levels in non infected control, set as 1. Placentas from each individual mouse were pooled. Five animals per group were analyzed. Results are expressed as mean +/− SD. *p<0.05 respect to uninfected control placentas. Representative data from 3 independent experiments.