Table 4. Organ colonization in pregnant and non pregnant hosts after S. Enteritidis enterocolitis.
Mice | Dose CFU/mice | Peyer's patches(a) CFU/organ | Spleen(a) CFU/organ | Intestine(a) CFU/organ | Uterus(a) CFU/organ | Placenta(a) CFU/organ | Fetus(a) CFU/fetus |
Pregnant | 103 | 5,8×105 * | 6,4×105 * | 4,0×104 ‡ | 4,9×105 | 2×105 | 7,6×102 |
(104–8×105) | (104–106) | (103–7×104) | (105–5×106) | (105–5 ×106) | (105–5×106) | ||
Non pregnant | 103 | 6×101 | 7×101 | 1.5×102 | - | - | - |
(2×101–8×101) | (2×101–9×101) | (2×101–3×102) |
Groups of 15 pregnant and non pregnant mice received 20 mg of streptomycin 24 h before intragastric infection with 3–4×103 CFU of S. Enteritidis (day 15 of gestation in case of pregnant hosts). At day 3 after infection mice were sacrificed and bacterial loads were analyzed as described in materials and methods.
Median (range).
*p<0.01;
p<0.05 in comparison with the non pregnant infected.