Table 1. Characteristics of study population, women with antidepressant treatment and delivery at Karolinska University Hospital Huddinge Jan 2007 to June 2009.
| All antidepressants | Citalopram | Sertraline | Fluoxetine | Other antidepressants** | |
| n = 220 | n = 77 (35%) | n = 76 (35%) | n = 34 (15%) | n = 33 (15%) | |
| Age of mother at delivery mean (years) | 31.2 | 31.2 | 32.1 | 29.4 | 31.0 |
| Maternal psychiatric diagnosis ≠ (n) | |||||
| Depression | 168 | 59 | 58 | 29 | 22 |
| Anxiety disorder | 80 | 29 | 27 | 8 | 16 |
| Other psychiatric diagnoses≠≠ | 34 | 7 | 12 | 10 | 5 |
| Tobacco in early pregnancy * (n [%]) | |||||
| No smoking | 189 (86%) | 69 (90%) | 62 (82%) | 29 (85%) | 29 (88%) |
| <10 cigarettes per day | 25 (11%) | 7 (9%) | 11 (14%) | 4 (12%) | 3 (9%) |
| >10 cigarettes per day | 4 (2%) | 1 (1%) | 2 (3%) | 1 (3%) | |
| Snuff | 2 (1%) | 1 (1%) | 1 (3%) | ||
| Employment status * (n [%]) | |||||
| Full time employed | 87 (40%) | 32 (42%) | 33 (43%) | 9 (26%) | 13 (39%) |
| Part time employed | 54 (25%) | 19 (25%) | 18 (24%) | 5 (15%) | 12 (36%) |
| Unemployed | 72 (33%) | 23 (30%) | 23 (30%) | 18 (53%) | 8 (24%) |
| Missing data | 7 (3%) | 3 (4%) | 2 (3%) | 2 (6%) | |
| Body mass index * mean (kg/m2) | 24.4 | 24.0 | 24.7 | 24.9 | 24.1 |
| Other illnesses * (n [%]) | 106 (48%) | 33 (43%) | 42 (55%) | 12 (35%) | 19 (58%) |
| Antidepressant dose in third trimester *** median (range) (mg) | NA | 20 (5–80) | 50 (5–200) | 30 (10–80) | NA |
| Use of benzodiazepine during pregnancy (n [%]) | 14 (6%) | 4 (5%) | 5 (7%) | 3 (9%) | 2 (6%) |
| Use of other medications during pregnancy (n [%]) | 136 (62%) | 43 (56%) | 44 (58%) | 27 (79%) | 22 (67%) |
| Mode of delivery (n [%]) | |||||
| Vaginal delivery | 155 (70%) | 57 (74%) | 48 (63%) | 25 (74%) | 25 (76%) |
| Cesarean section (planned) | 24 (11%) | 7 (9%) | 11 (14%) | 2 (6%) | 4 (12%) |
| Cesarian section (acute) | 20 (9%) | 5 (6%) | 9 (12%) | 4 (12%) | 2 (6%) |
| Vacuum extraction | 21 (10%) | 8 (10%) | 8 (11%) | 3 (9%) | 2 (6%) |
≠
one patient can have more than one diagnosis.
≠≠
other psychiatric diagnoses, all antidepressants (n): Phobia (4), Post-traumatic stress disorder (4), Eating disorder (9), Personality disorder (6), Obsessive compulsive disorder (7), Bipolar disorder type II (1), Attention deficit hyperactivity disorder (3).
*stated by mother at interview with midwife in prenatal care center, gestational week 10–14.
**other antidepressants (n = 33): escitalopram (13 patients), venlafaxine (11), paroxetine (8) and duloxetine (1).
***Highest dose in maternal care records during third trimester.
NA = not applicable.