Skip to main content
. 2014 Nov 3;9(11):e111408. doi: 10.1371/journal.pone.0111408

Figure 6. Schematic representation of mucin gene induction by Shigella.

Figure 6

As indicated, BMP-SMAD pathway induces MUC2 gene expression through the CDX2 transcription factor whereas SMAD4 directly influences MUC5AC gene. Our data thereby unveil a complex signaling mechanism underlying mucin gene induction by Shigella.