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. Author manuscript; available in PMC: 2015 Nov 3.
Published in final edited form as: Chembiochem. 2014 Aug 26;15(16):2353–2356. doi: 10.1002/cbic.201402343

Figure 1.

Figure 1

Toehold-mediated capture/release strategy of target DNA sequences. For a given target DNA sequence, a capture oligonucleotide is designed to complement the sequence with an additional 8 nt of unique sequence (toehold). The release oligonucleotide is 100% complementary to the capture oligonucleotide, allowing for release of the target sequence