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. 2014 Nov 3;9(11):e111658. doi: 10.1371/journal.pone.0111658

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© 2014 Choi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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In 535 primary GC, (A) high-MET mRNA was associated with poor OS compared to low-MET mRNA (P = .002), (B) MET overexpression was associated with poor OS compared to no overexpression (P = .001), and (C) MET gene amplification was associated with poor OS compared to no amplification (P = .005). In 199 metastatic lymph nodes, (D) high-MET mRNA was associated with poor OS compared to low-MET mRNA (P<.001), and (E) MET overexpression was associated with poor OS compared to no overexpression (P = .024). (F) In 199 matched primary tumors and metastatic LNs, concordantly positive and positive conversion groups were associated with poor OS compared to concordantly negative group (concordantly negative vs. negative conversion, P = .640; concordantly negative vs. positive conversion, P = .011; concordantly negative vs. concordantly positive, P<.001; concordantly positive vs. negative conversion, P = .137; concordantly positive vs. positive conversion, P = .382; negative conversion vs. positive conversion, P = .260).