Table 2. Clinicopathologic characteristics of gastric carcinoma patients according to MET mRNA expression status.
| Characteristics | MET mRNA status by RNA ISH | ||
| Low-MET mRNA | High-MET mRNA | P-value | |
| (score 0–2) | (score 3–4) | ||
| n = 516 (96.4%) | n = 19 (3.6%) | ||
| Mean age, y | 57.9 | 70 | .002 |
| Mean tumor size, cm | 5.64 | 7.62 | .006 |
| Gender, n (%) | .639 | ||
| Male | 354 (69.6) | 14 (73.7) | |
| Female | 162 (31.4) | 5 (26.3) | |
| Lauren classification, n (%) | .832 | ||
| Intestinal | 230 (44.6) | 8 (42.1) | |
| Diffuse/mixed | 286 (55.4) | 11 (57.9) | |
| Tumor invasion, n (%) | .392 | ||
| EGC | 113 (21.9) | 2 (10.5) | |
| AGC | 403 (78.1) | 17 (89.5) | |
| LN metastasis, n (%) | .014 | ||
| Absent | 277 (41.5) | 3 (15.8) | |
| Present | 391 (58.5) | 16 (84.2) | |
| Distant metastasis, n (%) | .001 | ||
| Absent | 612 (91.6) | 12 (63.2) | |
| Present | 56 (8.4) | 7 (36.8) | |
| TNM stage, n (%) | <.001 | ||
| I | 191 (28.6) | 1 (5.3) | |
| II | 201 (30.1) | 3 (15.8) | |
| III | 220 (32.9) | 8 (42.1) | |
| IV | 56 (8.4) | 7 (36.8) | |
Abbreviations: AGC, advanced gastric carcinoma; EGC, early gastric carcinoma; ISH, in situ hybridization; LN, lymph node; TNM, Tumor-Node-Metastasis.