Figure 1. Genetic organization of the ahpC locus in M. smegmatis mc2155 (A) and the upstream sequence of ahpC encompassing its promoter region and the putative cis-acting elements involved in the regulation of ahpC expression (B).
The lengths of the overlapping region between MSMEG_4892 and ahpC and the intergenic regions are given as the nucleotide numbers above the schematic diagram. The two inverted repeats, IR1 (Crp-binding site) and IR2 (putative FurA-binding site), are marked by the two head-facing arrows above their sequences. The putative promoter region of ahpC is boxed. The nucleotide reported to be the transcriptional start point (+1) of ahpC is shaded in gray [15]. The start codon of ahpC is underlined and the arrow above it indicates the transcriptional direction. The numbers on the left of the sequences indicate the positions of the leftmost nucleotides relative to the ahpC gene.