Skip to main content
. 2014 Nov 3;9(11):e111715. doi: 10.1371/journal.pone.0111715

Table 3. Associations of rs9362054 in RP1-90L14.1 with diabetic retinopathy (DR), proliferative diabetic retinopathy (PDR) and diabetic nephropathy (DN) in each stage and combined stages 1, 2 and 3, using logistic regression under genotype, dominant and recessive models after adjusting for sex, duration of diabetes and HbA1c.

DR PDR DN
Stage 1+2 Stage 1+2+3 Stage 1+2+3 Stage 1+2+3
Stage 1 Stage 2 Overallanalysis Meta-analysis Stage 3 Overallanalysis Meta-analysis Overallanalysis Meta-analysis Overallanalysis Meta-analysis
OR P OR P OR P OR Pmet Phet OR P OR P OR Pmet Phet OR P OR Pmet Phet OR P OR Pmet Phet
genotype modela 1.59 2.1×10−3 1.59 2.4×10−4 1.63 3.4×10−7 1.59 1.8×10−6 1.0×100 1.15 2.5×10−1 1.45 1.7×10−7 1.39 4.8×10−6 1.3×10−1 1.21 6.1×10−2 1.12 2.6×10−1 6.4×10−2 1.68 1.0×10−6 1.53 1.2×10−4 4.8×10−1
dominant model 1.54 3.5×10−2 1.67 3.7×10−3 1.68 9.3×10−5 1.61 1.9×10−4 7.5×10−1 1.11 5.0×10−1 1.41 4.1×10−4 1.36 1.2×10−3 1.3×10−1 1.23 1.4×10−1 1.17 2.7×10−1 3.5×10−1 1.85 9.3×10−5 1.79 4.4×10−4 4.8×10−1
recessive model 3.00 1.2×10−3 2.27 1.2×10−3 2.60 2.3×10−6 2.51 6.0×10−6 5.1×10−1 1.46 1.5×10−1 2.32 3.3×10−8 2.14 1.3×10−6 3.8×10−1 1.39 1.0×10−1 1.20 3.9×10−1 3.0×10−2 2.27 2.4×10−5 1.78 5.6×10−3 6.5×10−1
a

With additive genetic effect.