Table 3. Number of children with virological failure* over time.
Month 6 | Month 12 | p-values** | Odds Ratio(95%%CI) | |
Parent status | ||||
Both died | 12(38) | 6(21) | 0.872 | 0.9(0.4–2.0) |
At least one lives | 34(39) | 11(15) | ||
Caregiver's educational status | ||||
Completed at least Primary school | 17(37) | 9(19) | 0.678 | 0.6(0.3–3.1) |
Non educated | 30(39) | 16(20) | ||
Distance from healthcare center | ||||
Living in Kigali | 22(40) | 9(17) | 0.567 | 0.8(0.5–2.7) |
Outside of Kigali | 28(41) | 13(19) | ||
Age group | ||||
Age ≥5 years at cART initiation | 21(29) | 7(11) | 0.006 | 2.6(1.3–5.2) |
Age <5 years at cART initiation | 25(52) | 10(25) | ||
Immunological status at baseline | ||||
CD4≥15% or 350/mm3 | 21(34) | 6(12) | 0.282 | 1.5(0.7–2.9) |
CD4<15% or <350/mm3 | 23(43) | 10(20) | ||
WHO stage at baseline | ||||
Baseline WHO I&II | 8(35) | 0 | 0.171 | 1.7(0.8–3.9) |
Baseline WHO III&IV | 37(39) | 16(19) | ||
95% Adherence | ||||
Adherent | 26(32) | 12(15) | 0.009 | 2.5(1.3–5.0) |
Non-adherent | 20(53) | 5(24) | ||
PMTCT exposure | ||||
No-exposure | 26(31) | 9(12) | 0.003 | 3.4(1.5–7.9) |
Exposure | 14(58) | 6(38) | ||
Regimen switch up to 6 or 9 months | ||||
No treatment change | 40(37) | 12(14) | 0.337 | 1.6(0.6–4.3) |
Treatment change | 6(54) | 7(49) |
*Virological failure defined as VL≥1000 copies/mL for one measurement;
**between group comparisons.
P values bold: significant difference at p<0.05.