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. 2014 Nov 3;9(11):e111948. doi: 10.1371/journal.pone.0111948

Table 3. Number of children with virological failure* over time.

Month 6 Month 12 p-values** Odds Ratio(95%%CI)
Parent status
Both died 12(38) 6(21) 0.872 0.9(0.4–2.0)
At least one lives 34(39) 11(15)
Caregiver's educational status
Completed at least Primary school 17(37) 9(19) 0.678 0.6(0.3–3.1)
Non educated 30(39) 16(20)
Distance from healthcare center
Living in Kigali 22(40) 9(17) 0.567 0.8(0.5–2.7)
Outside of Kigali 28(41) 13(19)
Age group
Age ≥5 years at cART initiation 21(29) 7(11) 0.006 2.6(1.3–5.2)
Age <5 years at cART initiation 25(52) 10(25)
Immunological status at baseline
CD4≥15% or 350/mm3 21(34) 6(12) 0.282 1.5(0.7–2.9)
CD4<15% or <350/mm3 23(43) 10(20)
WHO stage at baseline
Baseline WHO I&II 8(35) 0 0.171 1.7(0.8–3.9)
Baseline WHO III&IV 37(39) 16(19)
95% Adherence
Adherent 26(32) 12(15) 0.009 2.5(1.3–5.0)
Non-adherent 20(53) 5(24)
PMTCT exposure
No-exposure 26(31) 9(12) 0.003 3.4(1.5–7.9)
Exposure 14(58) 6(38)
Regimen switch up to 6 or 9 months
No treatment change 40(37) 12(14) 0.337 1.6(0.6–4.3)
Treatment change 6(54) 7(49)

*Virological failure defined as VL≥1000 copies/mL for one measurement;

**between group comparisons.

P values bold: significant difference at p<0.05.