Table 2.

Scope of Pivalate^a

entry	1 (% ee)b	Product	yield (%)c	ee (%)d	es (%)e
1f,g			71	94	≥94
2g			93	97	≥97
3g			94	96	≥96
4h			72	91	98
5f,i			85	86	≥86
6f,i,j			96	80	≥80
7k			87	93	≥93
8			84	94	96
9			45	89	94
10			73	73	85
11			94	58	71
12l,m			49	72	88
13m,n			33	84	90

^aConditions: pivalate (0.20 mmol, 1.0 equiv), boroxine (0.83–1.3 equiv), Ni(cod)₂ (5 mol %), NaOMe (2.0 equiv), PhMe (0.4 M), 70 °C, 3 h, unless otherwise noted.

^bDetermined by chiral HPLC.

^cAverage isolated yield of duplicate experiments (±0–2%), unless otherwise noted.

^dDetermined by chiral HPLC. Average ee of duplicate experiments reported (±0–1%).

^e% es = enantiospecificity = (prod ee)/(SM ee)*100.

^f10 mol % Ni(cod)₂.

^g80 °C.

^h12 h.

ⁱ90 °C.

^jResult of a single experiment.

^k50 °C.

^l32 °C.

^m24 h.

ⁿ100 °C.