Table 1.
Analyzed polymorphisms in MET gene and the functional significance
| rs number | Location of polymorphism |
Base exchange |
Predictive function of polymorphism |
Forward primer (5’-3’) | Reverse primer (5’-3’) |
|---|---|---|---|---|---|
| rs41736 | Exon | C>T | Exonic Splicing Enhancer/Exonic Splicing Silencer | GGGAGCTGATGACAAGAGGA | AAGGGGTCTGGGCAGTATTC |
| rs41739 | 3'-UTR | A>G | MicroRNA binding | TTGGGGAGTTTTATTTTGCATT | TCAGGGTGGCTATTCCATCT |
| rs40239 | Intron | A>G | Tag SNP | GTTCCTATTGGCACGTGGTT | GCCATGATGGATTCAGGTTT |
| rs1621 | 3'-UTR | A>G | MicroRNA binding | AGGCAATTGAAAATCCCAGCT | GAGTAACCTACACCACATGCAC |
| rs10234854 | Intron | G>A | Tag SNP | GAGGCACATTCTGGTTCTATTGT | CCCCTCAAACTACCACCACT |
| rs184953 | 5’-UTR | C>A | Transcription Factor Binding | GCGGTGCCCAAATCTCTCTA | CTTGGGAGGCGAGTGTCA |