Table 3.
| GENE SYMBOL | REGULATION STATUS | BIOCHEMICAL PATHWAY | PROGNOSIS | REGULATORS |
|---|---|---|---|---|
| GRB2 | up | ERBB2 and PDGFRB | poor | MYC and STAT3 |
| CDKN1A | up | p53, cell cycle and ERBB2 | poor | MYC and STAT3 |
| ARAF | up | ERBB2 | poor | MYC and STAT3 |
| NCK2 | up | ERBB2 and PDGFRB | poor | MYC and STAT3 |
| PAK6 | up | ERBB2 | good | MYC and STAT3 |
| KRAS | up | ERBB2 and VEGF | good | MYC and STAT3 |
| STAT3 | up | PDGFRB and angiogenesis | poor | MYC and STAT3 |
| ELK1 | up | FOXC1 network and ERBB2 | good | MYC and STAT3 |
| OIP5 | down | FOXC1 network | good | MYC and STAT3 |
| *NRAS | up | ERBB2 | poor | STAT3 |
| LYN | up | PDGFRB and angiogenesis | poor | MYC and STAT3 |
| VEGFA | up | angiogenesis | poor | MYC and STAT3 |