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. 2014 Oct 20;5:5258. doi: 10.1038/ncomms6258

Figure 6. Optical coherence tomography through CLEAR and platinum devices.

Figure 6

(a,c) Maximum intensity projection (MIP) of OCT angiogram showing cortical vasculature visible through the CLEAR micro-ECoG device (FOV 2.8 × 2.8 mm2 and 1.1 × 1.1 mm2, respectively). (b,d) Doppler blood flow velocity image showing the directionality of blood flowing through the vasculature below the CLEAR device (FOV 2.8 × 2.8 mm2 and 1.1 × 1.1 mm2). Red colour represents blood flowing towards the lens and green colour represents blood flowing away. (e) Cross-sectional angiogram after contrast enhancement and de-shadowing (CLEAR device). (f) 3D visualization of the vasculature (red colour) overlaid on the structural data (grey) (CLEAR device). (g) MIP of angiogram through a platinum micro-ECoG device. (h) Corresponding Doppler blood flow velocity measurements. (i) Corresponding cross-sectional angiogram. (j) Corresponding 3D visualization of vessel structure for a micro-ECoG array with platinum electrode sites. Scale bars, 200 μm (a,b), 100 μm (c–i).