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. 2014 Oct 29;15(1):133. doi: 10.1186/s12931-014-0133-y

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© Bodine et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Bronchoalveolar lavage fluid (BALF) analysis revealed increased cellularity and percent PMNs in RAGE TG compared to control mice. RAGE TG mice did not have significant differences in total BALF protein when compared to controls (A). However, the total number of leukocytes detected in BALF was statistically increased in samples from RAGE TG mice compared to controls (B). A closer inspection of total cells in BALF revealed that the percentage of PMNs was significantly elevated in RAGE TG mice (C). N = 6 animals per group, *p ≤ 0.05.