Examples of laterality defects on radiology imaging in various situs groups in the study population. A, A participant with situs solitus, or normal organ arrangement, with left cardiac apex, left-sided stomach bubble, and right-sided liver. B, A patient with situs inversus totalis, or mirror-image organ arrangement, with right-sided cardiac apex, right-sided stomach bubble, and left-sided liver. C, A patient with situs ambiguus with left-sided cardiac apex, right-sided stomach bubble, right-sided liver, and intestinal malrotation who also has right-sided polysplenia visualized on CT scan. C = cardiac apex; L = liver; M = intestinal malrotation; S = stomach.