TABLE 3 ] .
Characterization of Hospitalizations, by Type of Hospitalization
| Parameter | PAH Related (A) | PAH Unrelated (B) | Alla (C) | P Value (A vs B) |
| No. of patientsb | 257 | 214 | 471 | … |
| Length of stay, d | ||||
| No. of patients | 248 | 202 | 450 | .13c |
| Mean (SD) | 6.5 (7.9) | 10.3 (38.7) | 8.2 (26.6) | … |
| Median | 4.0 | 4.0 | 4.0 | … |
| Length of stay ≥ 7 d, No. (%) | 73 (29.4) | 54 (26.7) | 127 (28.2) | .53d |
| Total hospital days in the year after first admission | ||||
| No. of patients | 248 | 202 | 450 | .47c |
| Mean (SD) | 14.3 (24.7) | 16.6 (42.6) | 15.3 (33.9) | … |
| Median | 7.5 | 6.5 | 7.0 | … |
| Total days ≥ 14 d, No. (%) | 74 (28.8) | 48 (22.4) | 122 (25.9) | .12d |
| No. of readmissions during study | ||||
| No. of patients | 257 | 214 | 471 | .42c |
| Mean (SD) | 1.8 (2.6) | 2.1 (3.7) | 1.9 (3.1) | … |
| None, No. (%) | 93 (36.2) | 90 (42.1) | 183 (38.9) | … |
| 1 readmission, No. (%) | 71 (27.6) | 47 (22.0) | 118 (25.1) | … |
| ≥ 2 readmissions, No. (%) | 93 (36.2) | 77 (36.0) | 170 (36.1) | … |
| Average length of follow-up from hospital discharge, y | ||||
| No. of patients | 241 | 211 | 452 | .91c |
| Mean (SD) | 2.2 (1.7) | 2.2 (1.5) | 2.2 (1.6) | … |
| Hospitalization rate, No. per year of follow-up | ||||
| No. of patients | 241 | 211 | 452 | .10c |
| Mean (SD) | 2.2 (5.6) | 1.5 (3.0) | 1.8 (4.6) | … |
| No. of PAH medications at admission, No. (%) | ||||
| None | 26 (10.1) | 26 (12.1) | 52 (11.0) | .82d |
| Monotherapy | 133 (51.8) | 106 (49.5) | 239 (50.7) | … |
| Double therapy | 79 (30.7) | 69 (32.2) | 148 (31.4) | … |
| Triple therapy | 19 (7.4) | 13 (6.1) | 32 (6.8) | … |
| Parenteral therapy | 111 (45.5) | 43 (21.6) | 154 (34.8) | < .001d |
| Warfarin use | 76 (29.9) | 48 (22.5) | 124 (26.6) | .072d |
| Diuretic use | 120 (47.2) | 85 (39.9) | 205 (43.9) | .11d |
| Most recent FC assessment prior to hospitalization, No. (%) | ||||
| FC I | 12 (4.9) | 7 (3.5) | 19 (4.3) | .003e |
| FC II | 58 (23.8) | 71 (35.9) | 129 (29.2) | … |
| FC III | 136 (55.7) | 107 (54.0) | 243 (55.0) | … |
| FC IV | 38 (15.6) | 13 (6.6) | 51 (11.5) | … |
| REVEAL Registry risk score prior to hospitalization | ||||
| No. of patients | 257 | 214 | 471 | .018c |
| Mean (SD) | 8.5 (2.3) | 8.0 (2.5) | 8.3 (2.4) | … |
| In-hospital death, No. (%) | 14 (5.4) | 3 (1.4) | 17 (3.6) | .024f |
a
All patients with ≥ 1 hospitalization (C) includes patients with PAH-related (A) and PAH-unrelated (B) hospitalizations. Nineteen patients with undetermined causes of hospitalization were not included in this cohort. FC = New York Heart Association functional class. See Table 1 legend for expansion of other abbreviation.
b
The total number of patients in each cohort with data at enrollment for each parameter is assumed to be 257 (A), 214 (B), and 471 (C), unless otherwise noted.
c
P value is computed using t test.
d
P value is computed using χ2 test.
e
P value is computed using Mantel-Haenszel test.
f
P value is computed using Fisher exact test.