Table 4.
Distribution of DRD2/ANKK1 rs1800497 alleles and DRD4 exon III variable number of tandems repeat alleles in relation to BMI among all adult and pediatric subjects
| |
Adults (lean) |
|
Children (overweight or obese) |
|
|||||
|---|---|---|---|---|---|---|---|---|---|
| N (% of total) n = 583 | Age | Sex | BMI | N (% of total) n = 451 | Age | Sex | BMI | BMI-SDS | |
|
rs1800497 |
|
|
|
|
|
|
|
|
|
| CC (A2/A2) |
407 (69.8) |
25.4 ± 4.5 |
161 M/246 F |
19.2 ± 2.0 |
308 (68.3) |
10.8 ± 2.6 |
139 M/169 F |
27.5 ± 4.5 |
2.4 ± 0.5 |
| CT (A1/A2) |
161 (27.6) |
25.1 ± 4.3 |
64 M/97 F |
19.1 ± 1.9 |
132 (29.3) |
10.7 ± 2.7 |
60 M/72 F |
27.2 ± 4.4 |
2.3 ± 0.5 |
| TT (A1/A1) |
15 (2.6) |
24.4 ± 3.0 |
6 M/9 F |
18.2 ± 1.1 |
11 (2.4) |
11.3 ± 1.7 |
4 M/7 F |
26.5 ± 2.5 |
2.1 ± 0.4 |
|
DRD4 7R+ |
|
|
|
|
|
|
|
|
|
| No |
357 (61.2) |
25.6 ± 4.6 |
149 M/208 F |
19.2 ± 2.0 |
285 (63.2) |
10.8 ± 2.6 |
135 M/150 F |
27.2 ± 4.4 |
2.3 ± 0.5 |
| One |
198 (34.0) |
24.8 ± 4.1 |
71 M/127 F |
19.0 ± 1.9 |
148 (32.8) |
10.8 ± 2.7 |
62 M/86 F |
27.4 ± 4.6 |
2.4 ± 0.5 |
| Two | 28 (4.8) | 25.4 ± 4.0 | 11 M/17 F | 18.8 ± 1.5 | 18 (4.0) | 11.4 ± 2.1 | 6 M/12 F | 29.0 ± 3.8 | 2.5 ± 0.3 |
Age and BMI values are Mean ± SD.