. Author manuscript; available in PMC: 2014 Nov 4.

Published in final edited form as: Vet J. 2012 Oct 23;196(2):266–268. doi: 10.1016/j.tvjl.2012.09.008

Table 2.

Hydromorphone pharmacokinetic parameters after a mean dose of 0.5 mg/kg hydrocodone bitartrate (equivalent to 0.3 mg/kg hydrocodone base) PO to six healthy Greyhounds.

Parameter	Units	Geometric Mean	Min	Median	Max
AUC _extrapolated	%	24.77	17.77	22.64	38.13
AUC _inf	h*ng/mL	37.17	30.29	37.49	41.72
C_MAX	ng/mL	5.20	3.54	5.01	8.61
T ½ λz	h	3.07	2.11	3.08	4.68
λz	1/h	0.226	0.148	0.242	0.329
MRT _inf	h	6.11	5.08	5.69	8.04
T_MAX	h	1.37	0.75	1.50	3.00
Vz/F	L/kg	36.21	20.68	39.63	55.61