Table 2.
Treatment Group |
Diameter X, nm |
Diameter Y, nm |
Area, 103 nm2 |
Circumference, nm |
---|---|---|---|---|
Sham | 198.4±1.9 | 195.5±1.9 | 30.6±0.4 | 656.5±5.6 |
4pMI | 205.7±2.9* | 210.1±3.2* | 34.3±0.8* | 692.6±9.5* |
8pMI | 213.0±3.4* | 219.9±3.3*† | 37.2±0.9*† | 748.9±11.2*† |
TT cross sections were imaged by STED deep inside cardiomyocytes each for sham, 4pMI, and 8pMI treatment groups. TT diameters represent FWHM measurements by automated 2D Gauss fitting corresponding to X (longitudinal) and Y (transversal). Circumference was determined by automated contour analysis. Data represent unpaired measurements.
P<0.05 versus sham;
P<0.05 versus 4pMI; mean±SEM from the following numbers of TT cross sections (cells) for each treatment group: sham, 627 (90); 4pMI, 237 (44); and 8pMI, 290 (46).