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. Author manuscript; available in PMC: 2014 Nov 4.
Published in final edited form as: Circ Res. 2012 Jun 21;111(4):402–414. doi: 10.1161/CIRCRESAHA.112.274530

Table 2.

Intracellular TT Cross-Section Dimensions 4 Weeks or 8 Weeks After Myocardial Infarction Compared With Sham Control Treatment

Treatment
Group
Diameter X,
nm
Diameter Y,
nm
Area,
103 nm2
Circumference,
nm
Sham 198.4±1.9 195.5±1.9 30.6±0.4 656.5±5.6
4pMI 205.7±2.9* 210.1±3.2* 34.3±0.8* 692.6±9.5*
8pMI 213.0±3.4* 219.9±3.3* 37.2±0.9* 748.9±11.2*

TT cross sections were imaged by STED deep inside cardiomyocytes each for sham, 4pMI, and 8pMI treatment groups. TT diameters represent FWHM measurements by automated 2D Gauss fitting corresponding to X (longitudinal) and Y (transversal). Circumference was determined by automated contour analysis. Data represent unpaired measurements.

*

P<0.05 versus sham;

P<0.05 versus 4pMI; mean±SEM from the following numbers of TT cross sections (cells) for each treatment group: sham, 627 (90); 4pMI, 237 (44); and 8pMI, 290 (46).