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. 2013 Oct 16;1:1500210. doi: 10.1109/JTEHM.2013.2285916

Table I. The Effects of Metabolic Inhibitors and Uncoupler on the Lung Tissue Surface FAD and NADH Fluorescence Signals of Normoxic and Hyperoxic Rats.

Inhibitor/ Uncoupler FAD % NADH %
Normoxic Hyperoxic Normoxic Hyperoxic
Rotenone 0.2 ± 0.2 −0.3 ± 0.3 20.2 ± 2.3 7.5 ± 1.0*
KCN −6.8 ± 1.6 −5.2 ± 0.5 21.7 ± 2.5 9.2 ± 1.2*
PCP 1.7 ± 0.8 −2.3 ± 1.4* −19.7 ± 2.1 −20.8± 1.2
PCP + KCN −9.3 ± 1.0 −4.2 ± 0.7 * 25.7 ± 2.6 9.0 ± 1.0*
Rotenone + KCN 0.8–3.3 ± −3.8 ± 0.6 4.6 ± 1.0 2.8 ± 1.2

Values are mean ± SE. For the (PCP + KCN) and (rotenone + KCN) treatments, the percentage change due to additional treatment with KCN is calculated relative to the new baseline in the presence of PCP or rotenone, respectively. For normoxic lungs, Inline graphic and 5 for rotenone, potassium cyanide (KCN), pentachlorophenol (PCP), PCP + KCN, and rotenone + KCN, respectively. For hyperoxic lungs Inline graphic, and 4 for rotenone, KCN, PCP, PCP + KCN, and rotenone + KCN, respectively.

* indicates value significantly different from the corresponding normoxic value (t-test Inline graphic).