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. Author manuscript; available in PMC: 2014 Nov 4.
Published in final edited form as: Basic Clin Pharmacol Toxicol. 2007 Oct;101(4):262–268. doi: 10.1111/j.1742-7843.2007.00116.x

Fig. 3.

Fig. 3

Effects of silymarin on palmitate-induced caspase-3 activation in HepG2 cell. (A) Caspase-3 inhibitor inhibited palmitate-induced cell death in HepG2. Apoptosis was measured by DNA fragmentation ELISA assay and expressed as fold of untreated. At least three experiments were conducted for each measurement. Values in bars that do not share a letter differ significantly, P < 0.05. Both (B) enzymatic activity assay and (C) Western blot analysis indicated that silymarin pre-treatments prevented palmitate-induced caspase-3 activation. *Value is statistically different from that seen in the absence of silymarin, P < 0.05.