Table 7.

Significant SNPs in the genome-wide association study of a single substance dependence from association tests. op: opiates; oth: other drugs.

Chr	SNP	MAF	Gene	p-values
				T	T W,1	T W,2	${\widehat{T}}_{\text{IPW}}$
op
Black Men
2	rs2377339	0.019	NCK2	1.1e-8	1.1e-9	1.4e-9	8.2e-9
16	rs2042360	0.066	–	9.2e-7	6.5e-8	4.3e-7	9.6e-7
17	rs17544779	0.017	–	5.6e-8	6.3e-6	1.8e-6	4.6e-8
White Men
13	rs9529180	0.111	PCDH9	1.5e-7	4.6e-7	4.9e-8	1.1e-7
13	rs9540995	0.112	PCDH9	2.2e-7	7.0e-7	5.9e-8	1.5e-7
13	rs9529185	0.111	PCDH9	1.6e-7	4.7e-7	5.2e-8	1.1e-7
Black Women
5	rs2441010	0.012	–	1.0e-7	1.1e-4	8.2e-5	7.6e-8
7	rs2528381	0.084	UBE2D4	1.9e-5	5.1e-8	2.9e-5	1.6e-5
7	rs1182398	0.014	UBE3C	1.9e-7	5.6e-8	1.2e-6	1.1e-7
10	rs7911634	0.011	PCDH15	7.2e-5	2.7e-9	3.1e-6	6.6e-5
14	rs17197261	0.020	0R10G3	1.3e-5	4.5e-8	1.4e-3	1.0e-5
White Women
19	rs3745816	0.016	EML2	2.2e-5	4.4e-11	2.0e-5	1.3e-5
19	rs4445998	0.015	EML2	1.2e-5	1.2e-11	2.4e-5	6.7e-6
19	rs1545040	0.020	EML2	1.5e-3	5.7e-8	2.5e-3	1.1e-3
oth
Black Women
11	rs11603357	0.041	–	2.5e-7	2.6e-8	1.1e-8	1.5e-7
White Women
17	rs3098945	0.187	ANKRD13B	4.5e-6	1.8e-8	6.0e-7	1.1e-6